Introducing a static receptor to compete with a dynamic combinatorial library in template binding.
作者： Filip Ulatowski , Dawid Lichosyt , Janusz Jurczak
DOI: 10.1039/C5OB01698C
关键词: Competition (economics) 、 Dynamic combinatorial chemistry 、 Hplc analysis 、 Computational biology 、 Chemistry 、 Receptor 、 Association (object-oriented programming) 、 Bioinformatics
摘要: We show herein that establishing a competition between static receptor and components of dynamic combinatorial libraries to bind an appropriately selected template can be used determine association constants by HPLC analysis after freezing the equilibrium.
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