Exact and Approximation Algorithms for Sorting by Reversals, with Application to Genome Rearrangement

作者: J. Kececioglu , D. Sankoff

DOI: 10.1007/BF01188586

关键词: PermutationApproximation algorithmSeries (mathematics)Theory of computationSubstringSortingCombinatoricsEdit distanceChromosomal inversionMathematics

摘要: Motivated by the problem in computational biology of reconstructing series chromosome inversions which one organism evolved from another, we consider computing shortest reversals that transform permutation to another. The permutations describe order genes on corresponding chromosomes, and areversal takes an arbitrary substring elements, reverses their order.

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