Leishmaniasis vaccine candidates for development: a global overview.

作者: Ali Khamesipour , Noushin Davoudi , Sima Rafati , Farrokh Modabber , Fereidoun Maboudi

DOI:

关键词: Clinical immunologyLeishmaniasisEconomic growthHuman useLeishmaniasis VaccinesLeishmania speciesPublic healthVisceral leishmaniasisWorld health

摘要: A vaccine against different forms of leishmaniasis should be feasible considering the wealth information on genetics and biology parasite, clinical experimental immunology leishmaniasis, availability vaccines that can protect animals challenge with Leishmania species. However, there is no any form for general human use. One major factor lack a conceived market vaccines. Hence pharmaceutical industries involved in development are not interested investing millions dollars decade required developing new vaccine. Besides, local/regional problem global one. According to estimates World Health Organization, 90 per cent visceral occurs five countries (Bangladesh, Brazil, India, Nepal Sudan). Those need amongst poorest people these countries. It therefore objectives develop Fortunately, both Brazil India have designated control as top priority their respective Ministries Health. The purpose this review present only use those dogs or humans. This an exhaustive discovery principles underlying development.

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