Some effects of vitamin E deficiency on hepatic xanthine dehydrogenase activity, lead, and α-tocopherol concentrations in tissues of lead-dosed mallard ducks☆

摘要: Abstract Three experiments were conducted to determine whether vitamin E deficiency (−E) and/or the oral administration of lead (300 mg/kg body weight) mallard ducks would affect hepatic xanthine dehydrogenase (XDH) activity and tissue deposition. Although there was a significant difference between +E −E plasma α-tocopherol (PαT) liver (LαT) concentrations in Experiment 1, XDH unaffected. In 2, 1-day-old ducklings fed experimental diets for 14 days then given (Pb). Forty-eight hours after dosing with Pb results obtained similar those 1 except that LαT distinctly elevated per gram wet weight significantly depressed Pb-treated groups. With treatment whole blood content markedly increased. After 96 hr, blood, liver, kidney, spleen +E+Pb group greater than −E+Pb group. 3, 30-week-old, E-depleted drakes above showed normal but marked differences PαT observed. Again signficantly It appears is not responsive deficiency. Also content, exception drake concentrations, seems be positively related status.