Human metapneumovirus infection in Thai children

作者: Wanida Thanasugarn , Rujipat Samransamruajkit , Pijitra Vanapongtipagorn , Nuanchan Prapphal , Bernadette Van Den Hoogen

DOI: 10.1080/00365540310000094

关键词: Human metapneumovirus infectionGenotypeImmunologyClinical significanceHuman metapneumovirusTypingRespiratory tractBiologyEl NiñoPolymerase chain reaction

摘要: Human metapneumovirus (hMPV) associated with clinical respiratory tract infection (RTI) in children was first isolated the Netherlands. Of 120 Thai paediatric patients RTI examined, 5 cases (4.2%) showed detectable hMPV based on N-gene-specific RT-PCR. All of them were negative for hRSV infection. Aligning sequences a reference strain revealed some nucleotide differences, which necessitates future investigation to evaluate significance and genotype variation.

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