The characteristics of post-neurosurgical bacterial meningitis in elective neurosurgery in 2012: A single institute study

摘要: Abstract Objective Most post-neurosurgical meningitis research has been focused on large cohorts with numerous cases followed over several years. However, the characteristics of in an entire single year are still unclear, and knowledge these might influence selection appropriate antibiotics therapeutic strategies for successful management this disease. Our aim is to obtain a better understanding year. Materials methods Patients positive cultures after neurosurgical operations our hospital during 2012 were included analysis. We report demographic characteristics, morbidity different seasons, clinical bacteriological profiles, sensitivity causes infections cohort. Results Of 6407 patients who underwent procedures study period, 146 developed overall incidence was 2.28%. The significantly higher surgery autumn winter than spring or summer ( p =0.000). most common organisms causing Gram-positive bacteria, by Klebsiella Baumannii species. Compound sulfamethoxazole (52.6%) vancomycin (10.5%) active against bacteria strains, whereas meropenem (43.8%) polymyxin (18.8%) Gram-negative bacillus strains. Conclusions Post-neurosurgical usually occurs hospital. organisms, which sensitive compound vancomycin, causative pathogens northern mainland China.