Antiöstrogene Therapie des metastasierenden Mammakarzinoms

摘要: Within a period of four years 35 patients with metastatic breast cancer were treated tamoxifen. One third had objective remissions, average duration complete remission being 30.6 months and partial 13.7 months. Mean survival time from start tamoxifen treatment in five was while seven it 20.4 Nine unresponsive metastases mean 24.3 months, the remaining 14 who deteriorated surviving for 11.7 Ten 12 responded well over 60 old. Lymph-node lung or pleural significantly reduced by eight six 15 cases, respectively. Satisfactory regression bony never seen. Because this, combined (10 mg twice daily) methandrostenolone (1 given to an additional patients, one them responding. Side effects included thrombocytopenia hypercalcaemia.