Preparation of highly hydrophilic magnetic nanoparticles with anion-exchange ability and their application for the extraction of non-steroidal anti-inflammatory drugs in environmental samples.

摘要: Diallyldimethylammonium chloride modified magnetic nanoparticles were synthesized by the “thiol-ene” click chemistry reaction. rendered material plenty of quaternary ammonium groups, and thus excellent aqueous dispersibility anion-exchange capability. The novel was then used as solid-phase extraction sorbent to extract eight non-steroidal anti-inflammatory drugs from water samples. Combined with high-performance liquid chromatography ultraviolet detection, under optimal conditions, developed method exhibited wide linearity ranges (1–1000, 2–1000 5–1000 ng mL−1) recoveries 88.0–108.6% low limits detection (0.3–1.5 ng mL−1). Acceptable precision obtained satisfactory intra-day inter-day relative standard deviations 0.4–4.4% (n = 3) 1.1–5.5% (n = 3), respectively. Batch-to-batch reproducibility acceptable deviations < 9.7%. hydrophilic nanoparticle featured groups showed high analytical potential for acidic analytes in environmental samples. This article is protected copyright. All rights reserved