作者: Jonathan M. Samet , Richard W. Hornung
DOI: 10.1111/J.1539-6924.1990.TB01021.X
关键词: Radon 、 Toxicology 、 Lung cancer 、 Epidemiology 、 Indoor air quality 、 Medicine 、 Risk assessment 、 Population 、 Environmental health 、 Hazard 、 Environmental exposure
摘要: Radon, a long-established cause of lung cancer in uranium and other underground miners, has recently emerged as potentially important the general population. The evidence for widespread exposure population to radon well-documented excess among miners exposed decay products have raised concern that progeny might also be To date, epidemiological data on risk associated with environmental been limited. Consequently, hazard posed by indoor air addressed primarily through estimation procedures. quantitative risks estimated using exposure-response relations derived from investigations miners. We review five more informative studies recent projection models radon. principal differ substantially their underlying assumptions consequently resulting projections. diversity illustrates substantial uncertainty remains concerning most appropriate model temporal pattern radon-related cancer. Animal experiments, further follow-up miner cohorts, well-designed should reduce this uncertainty.