Hospitalization for caffeine abuse is associated with abuse of other pharmaceutical products.
作者： Danielle M. McCarthy , Mark B. Mycyk , Carol A. DesLauriers
DOI: 10.1016/J.AJEM.2007.10.018
关键词: Caffeine 、 Concomitant 、 Poison control 、 Young adult 、 Surgery 、 Internal medicine 、 Odds ratio 、 Medicine 、 Intensive care 、 Retrospective cohort study 、 Cohort
摘要: Abstract Study Objective The aim of this study was to examine the characteristics and outcomes patients seeking treatment for abuse supplemental caffeine. Methods This a 3-year analysis conducted all consecutive cases involving caffeine in 10 years older reported regional poison center. Excluded were suicide attempts, therapeutic errors, only coffee or tea product. Results Two hundred fifty-four met inclusion criteria. Mean age 20.5 years, 50% women. Caffeine form nondietary medication 201 cases, dietary supplement 35 caffeine-enhanced beverage cases. abused alone 174 (68%), with alcohol 7, illegal drugs 6 other pharmaceutical products 81 (29%) Thirty-four (13% total) hospitalized medical complications from Only concomitant associated hospitalization (odds ratio, 3.8; 95% CI, 1.8-8.8; P = .0004). Conclusion In cohort, primarily by young adults. Concomitant recreational pharmaceuticals warrants further investigation.
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G E Bigelow, R R Griffiths, I A Liebson, Human coffee drinking: reinforcing and physical dependence producing effects of caffeine. Journal of Pharmacology and Experimental Therapeutics. ,vol. 239, pp. 416- 425 ,(1986)
O. Cauli, M. Morelli, Caffeine and the dopaminergic system. Behavioural Pharmacology. ,vol. 16, pp. 63- 77 ,(2005) , 10.1097/00008877-200503000-00001
Sarah Kerrigan, Tania Lindsey, Fatal caffeine overdose: Two case reports Forensic Science International. ,vol. 153, pp. 67- 69 ,(2005) , 10.1016/J.FORSCIINT.2005.04.016
Aaron B. Rosenblatt, Nagy A. Mekhail, Management of pain in addicted/illicit and legal substance abusing patients. Pain Practice. ,vol. 5, pp. 2- 10 ,(2005) , 10.1111/J.1533-2500.2005.05102.X
Joel V. Oberstar, Gail A. Bernstein, Paul D. Thuras, Caffeine use and dependence in adolescents: one-year follow-up. Journal of Child and Adolescent Psychopharmacology. ,vol. 12, pp. 127- 135 ,(2002) , 10.1089/104454602760219162
Juan A Carrillo, Julio Benitez, None, Clinically significant pharmacokinetic interactions between dietary caffeine and medications. Clinical Pharmacokinectics. ,vol. 39, pp. 127- 153 ,(2000) , 10.2165/00003088-200039020-00004
O. Emohare, V. Ratnam, Multiple cardiac arrests following an overdose of caffeine complicated by penetrating trauma. Anaesthesia. ,vol. 61, pp. 54- 56 ,(2006) , 10.1111/J.1365-2044.2005.04430.X
Lloyd D. Johnston, Patrick M. O’Malley, Jerald G. Bachman, Monitoring the Future: National Results on Adolescent Drug Use: Overview of Key Findings FOCUS. ,vol. 1, pp. 213- 234 ,(2003) , 10.1176/FOC.1.2.213
Per Holmgren, Lotta Nordén-Pettersson, Johan Ahlner, Caffeine fatalities—four case reports Forensic Science International. ,vol. 139, pp. 71- 73 ,(2004) , 10.1016/J.FORSCIINT.2003.09.019
Eric H Gilbert, Steven R Lowenstein, Jane Koziol-McLain, Diane C Barta, John Steiner, Chart Reviews In Emergency Medicine Research: Where Are The Methods? Annals of Emergency Medicine. ,vol. 27, pp. 305- 308 ,(1996) , 10.1016/S0196-0644(96)70264-0