Trichinella spiralis: modifications of the cuticle of the newborn larva during passage through the lung.

作者: Fabrizio Bruschi , Stefano Solfanelli , Ruben A. Binaghi

DOI: 10.1016/0014-4894(92)90116-R

关键词: CuticleTrichinellaParasite hostingPathologyNematodeIV injectionLungBiologyTrichinella spiralisLarvaAndrology

摘要: A scintigraphic method was developed to study the distribution of radioactivity after iv injection 131I-labeled Trichinella spiralis newborn larvae into normal rats. It found that immediately retained in lungs and thereafter slowly released, with a mean transit time excess 9 hr, as calculated by image analysis. At various times mice, were removed parasites recovered counted. Fifty seventy percent injected 30 sec, between 10 30% 1 min, less than 4% at 15 min. These results indicate during very rapid passage through lungs, labeled components cuticle are detached retained. is suggested modifications produced larva its lung may increase resistance nonspecific defense mechanisms host.

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