Chm-1 gene-modified bone marrow mesenchymal stem cells maintain the chondrogenic phenotype of tissue-engineered cartilage
作者： Zhuoyue Chen , Jing Wei , Jun Zhu , Wei Liu , Jihong Cui
DOI: 10.1186/S13287-016-0328-X
关键词: Cell biology 、 Tissue engineering 、 Mesenchymal stem cell 、 Stem cell transplantation for articular cartilage repair 、 Clinical uses of mesenchymal stem cells 、 Adult stem cell 、 Biology 、 Chondrogenesis 、 Amniotic stem cells 、 Cartilage
摘要: Background Marrow mesenchymal stem cells (MSCs) can differentiate into specific phenotypes, including chondrocytes, and have been widely used for cartilage tissue engineering. However, grafts from MSCs exhibit phenotypic alternations after implantation, matrix calcification vascular ingrowth.
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