Nuclei segmentation in histopathology images using deep neural networks

作者: Peter Naylor , Marick Lae , Fabien Reyal , Thomas Walter

DOI: 10.1109/ISBI.2017.7950669

关键词: Artificial neural networkBenchmark (computing)Digital pathologyArtificial intelligenceSet (abstract data type)Data setComputer visionImage segmentationHistopathologyCancerComputer science

摘要: Analysis and interpretation of stained tumor sections is one of the main tools in cancer diagnosis and prognosis, which is mainly carried out manually by pathologists. The avent of digital pathology provides us with the challenging opportunity to automatically analyze large amounts of these complex image data in order to draw biological conclusions from them and to study cellular and tissular phenotypes at a large scale. One of the bottlenecks for such approaches is the automatic segmentation of cell nuclei from this type of image data. Here …

参考文章(11)
Hyeonwoo Noh, Seunghoon Hong, Bohyung Han, Learning Deconvolution Network for Semantic Segmentation international conference on computer vision. pp. 1520- 1528 ,(2015) , 10.1109/ICCV.2015.178
Philipp Fischer, Thomas Brox, None, U-Net: Convolutional Networks for Biomedical Image Segmentation medical image computing and computer assisted intervention. pp. 234- 241 ,(2015) , 10.1007/978-3-319-24574-4_28
Jonathan Long, Evan Shelhamer, Trevor Darrell, Fully convolutional networks for semantic segmentation computer vision and pattern recognition. pp. 3431- 3440 ,(2015) , 10.1109/CVPR.2015.7298965
Baochuan Pang, Yi Zhang, Qianqing Chen, Zhifan Gao, Qinmu Peng, Xinge You, Cell Nucleus Segmentation in Color Histopathological Imagery Using Convolutional Networks chinese conference on pattern recognition. pp. 1- 5 ,(2010) , 10.1109/CCPR.2010.5659313
Humayun Irshad, Antoine Veillard, Ludovic Roux, Daniel Racoceanu, Methods for Nuclei Detection, Segmentation, and Classification in Digital Histopathology: A Review—Current Status and Future Potential IEEE Reviews in Biomedical Engineering. ,vol. 7, pp. 97- 114 ,(2014) , 10.1109/RBME.2013.2295804
Michel Grimaud, New measure of contrast: the dynamics Image Algebra and Morphological Image Processing III. ,vol. 1769, pp. 292- 305 ,(1992) , 10.1117/12.60650
Elisa Drelie Gelasca, Jiyun Byun, Boguslaw Obara, B.S. Manjunath, Evaluation and benchmark for biological image segmentation international conference on image processing. pp. 1816- 1819 ,(2008) , 10.1109/ICIP.2008.4712130
Paul A. Yushkevich, Joseph Piven, Heather Cody Hazlett, Rachel Gimpel Smith, Sean Ho, James C. Gee, Guido Gerig, User-guided 3D active contour segmentation of anatomical structures: Significantly improved efficiency and reliability NeuroImage. ,vol. 31, pp. 1116- 1128 ,(2006) , 10.1016/J.NEUROIMAGE.2006.01.015
Dan Ciresan, Jürgen Schmidhuber, Alessandro Giusti, Luca M. Gambardella, Deep Neural Networks Segment Neuronal Membranes in Electron Microscopy Images neural information processing systems. ,vol. 25, pp. 2843- 2851 ,(2012)
Jun Xu, Lei Xiang, Qingshan Liu, Hannah Gilmore, Jianzhong Wu, Jinghai Tang, Anant Madabhushi, Stacked Sparse Autoencoder (SSAE) for Nuclei Detection on Breast Cancer Histopathology Images IEEE Transactions on Medical Imaging. ,vol. 35, pp. 119- 130 ,(2016) , 10.1109/TMI.2015.2458702