Lithium and psychosis revisited.

摘要: Abstract 1. Using differential response to medications may help in resolving the central problem of heterogeneity psychoses, 2. A distinct subgroup patients with a lithium responsive, nonaffective psychosis has been shown have their core psychotic (nonaffective) symptoms respond alone. 3. The family histories psychoses suggests that there is less genetic loading for this patients. 4. Research on prodromal adjustment not reported. 5. Lithium responsive showed significantly fewer negative than did those who lithium. 6. Patients more extreme vitro ratios red blood cells and all types phospholipid methylation. 7. greater reduction during physostigmine challenge test, but results from apomorphine tests could be replicated. 8. Aside lithium, research difference treatment outcome group 9. Preliminary evidence suggest phenocopy other disorders associated ventriculomegaly stimulant abuse. 10. Lithium's effects acetylcholine as well dopamine serotonin explain its efficacy 11. This review supports existence separate disorder, further necessary. 12. appears separate, phenocopy.