Ileal pouch-anal canal anastomosis for familial adenomatous polyposis: early and late results.

摘要: Objective The objective was to review the early and late results of ileal pouch-anal anastomosis (IPAA) done for patients with familial adenomatous polyposis (FAP). Background Data Patients FAP will have colorectal adenomas develop die cancer if left untreated. Ileal removes all disease-bearing mucosa while preserving transanal passage stools. Methods Between 1981 1994, 187 FAP, 11 59 years age a mean follow-up 60 months (range, 5-170 months) had proctocolectomy IPAA at Mayo Medical Center in Rochester, Minnesota. All proximal anal canal mucosal excision hand-sewn pouch dentate line. A temporary ileostomy used 85% patients. Results No postoperative deaths occurred, although two died later metastatic carcinoma present their initial operation. More important, no patient new after IPAA. overall morbidity operation 24%, small bowel obstruction being most common complication (13%). four movements/24 hours good fecal control, which continued during follow-up. Conclusions eradicates risk FAP. It can be performed low mortality, acceptable morbidity, functional over long term.