Disulfide stabilised multivalent antibodies
作者： Ralph Adams , Laura Hancock , Sam Phillip Heywood
DOI:
关键词: Antibody 、 Fusion protein 、 Chemistry 、 Primary and secondary antibodies 、 Moiety 、 Antigen 、 Disulfide bond 、 Biochemistry 、 Antibody fragments
摘要: A multivalent antibody fusion protein which comprises an immunoglobulin moiety, for example a Fab or Fab' fragment, with first specificity antigen of interest, and further two single domain antibodies (dAb) second interest are VH/VL pair, wherein the linked by disulfide bond. Also provided particular dual proteins other fragments stabilised
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