Early life stress induces a transient increase in hippocampal corticotropin-releasing hormone in rat neonates that precedes the effects on hypothalamic neuropeptides.

作者: Naima Lajud , Angélica Roque , Edel Pineda , Kinberli Marcela Valles Méndez , Roberto Ruiz

DOI: 10.1111/EJN.15193

关键词: BiologySynaptophysinSynaptic plasticityEndocrinologyInternal medicineVasopressinHippocampusCorticotropin-releasing hormoneHippocampal formationCorticosteroneOxytocin

摘要: Early life stress (ELS) programs hypothalamus‐pituitary‐adrenal (HPA) axis activity and affects synaptic plasticity and cognitive performance in adults; however, the effects of ELS …

参考文章(62)
CHRISTINE HEIM, MICHAEL J. OWENS, PAUL M. PLOTSKY, CHARLES B. NEMEROFF, The role of early adverse life events in the etiology of depression and posttraumatic stress disorder Annals of the New York Academy of Sciences. ,vol. 821, pp. 194- 207 ,(1997) , 10.1111/J.1749-6632.1997.TB48279.X
J. J. Dimatelis, I. M. Vermeulen, K. Bugarith, D. J. Stein, V. A. Russell, Female rats are resistant to developing the depressive phenotype induced by maternal separation stress Metabolic Brain Disease. ,vol. 31, pp. 109- 119 ,(2016) , 10.1007/S11011-015-9723-8
Manila Loi, JCL Mossink, GF Meerhoff, JL Den Blaauwen, PJ Lucassen, M Joëls, None, Effects of early-life stress on cognitive function and hippocampal structure in female rodents. Neuroscience. ,vol. 342, pp. 101- 119 ,(2017) , 10.1016/J.NEUROSCIENCE.2015.08.024
Xue-Mei Liao, Xiao-Dun Yang, Jiao Jia, Ji-Tao Li, Xiao-Meng Xie, Yun-Ai Su, Mathias V. Schmidt, Tian-Mei Si, Xiao-Dong Wang, Blockade of corticotropin-releasing hormone receptor 1 attenuates early-life stress-induced synaptic abnormalities in the neonatal hippocampus Hippocampus. ,vol. 24, pp. 528- 540 ,(2014) , 10.1002/HIPO.22254
Paul M. Plotsky, Charles B. Nemeroff, Christine Heim, Michael J. Owens, Persistent changes in corticotropin-releasing factor systems due to early life stress: relationship to the pathophysiology of major depression and post-traumatic stress disorder Psychopharmacology Bulletin. ,vol. 33, pp. 185- 192 ,(1997)
Xiujing Cao, Shenghai Huang, Jiejie Cao, Tingting Chen, Ping Zhu, Rui Zhu, Puyu Su, Diyun Ruan, The timing of maternal separation affects morris water maze performance and long-term potentiation in male rats Developmental Psychobiology. ,vol. 56, pp. 1102- 1109 ,(2014) , 10.1002/DEV.21130
Michael J. Meaney, David H. Aitken, Victor Viau, Shakti Sharma, Alain Sarrieau, Neonatal handling alters adrenocortical negative feedback sensitivity and hippocampal type II glucocorticoid receptor binding in the rat. Neuroendocrinology. ,vol. 50, pp. 597- 604 ,(1989) , 10.1159/000125287