Bioinorganic modeling chemistry of carbon monoxide dehydrogenases: description of model complexes, current status and possible future scopes

摘要: Carbon monoxide dehydrogenases (CODHs) use CO as their sole source of carbon and energy are found in both aerobic anaerobic carboxidotrophic bacteria. Reversible transformation to CO2 is catalyzed by a bimetallic [Mo–(μ2-S)–Cu] system highly asymmetric [Ni–Fe–S] cluster CODH active sites. The activity the microorganisms effects removal almost 108 tons annually from lower atmosphere earth thus help maintain sub-toxic concentration CO. Despite an appreciable amount work, mechanism not clearly understood yet. Moreover, biomimetic chemistry directed towards sites CODHs faces several synthetic challenges. problems associated with modeling strategies adopted overcome those discussed along limitations. A critical analysis exciting results delineating present status its future prospects presented.