Effect of chronic exposure to rimonabant and phytocannabinoids on anxiety-like behavior and saccharin palatability
作者： Lesley D. O'Brien , Kiri L. Wills , Blair Segsworth , Brittany Dashney , Erin M. Rock
DOI: 10.1016/J.PBB.2012.10.008
关键词: Saccharin 、 Inverse agonist 、 Rimonabant 、 Cannabidiol 、 Palatability 、 Cannabigerol 、 Pharmacology 、 Chemistry 、 Tetrahydrocannabivarin 、 Cannabinoid
摘要: … Indeed, THCV shares the ability of the CB 1 inverse agonist/antagonist, AM251, to reduce the food intake and body weight of non-fasted and fasted mice but at lower doses (3 mg/kg) …
elsevier.com
sci-hub.se 参考文章(58)
Stephen V Mahler, Kyle S Smith, Kent C Berridge, Endocannabinoid hedonic hotspot for sensory pleasure: Anandamide in nucleus accumbens shell enhances 'liking' of a sweet reward Neuropsychopharmacology. ,vol. 32, pp. 2267- 2278 ,(2007) , 10.1038/SJ.NPP.1301376
Raphael Mechoulam, Linda A. Parker, The Endocannabinoid System and the Brain Annual Review of Psychology. ,vol. 64, pp. 21- 47 ,(2013) , 10.1146/ANNUREV-PSYCH-113011-143739
M JARRETT, C LIMEBEER, L PARKER, Effect of Δ9-tetrahydrocannabinol on sucrose palatability as measured by the taste reactivity test Physiology & Behavior. ,vol. 86, pp. 475- 479 ,(2005) , 10.1016/J.PHYSBEH.2005.08.033
John D. Salamone, Peter J. McLaughlin, Kelly Sink, Alexandros Makriyannis, Linda A. Parker, Cannabinoid CB1 receptor inverse agonists and neutral antagonists: effects on food intake, food-reinforced behavior and food aversions. Physiology & Behavior. ,vol. 91, pp. 383- 388 ,(2007) , 10.1016/J.PHYSBEH.2007.04.013
Robin Christensen, Pernelle Kruse Kristensen, Else Marie Bartels, Henning Bliddal, Arne Astrup, Efficacy and safety of the weight-loss drug rimonabant: a meta-analysis of randomised trials The Lancet. ,vol. 370, pp. 1706- 1713 ,(2007) , 10.1016/S0140-6736(07)61721-8
P. J. McLaughlin, K. M. Winston, C. L. Limebeer, L. A. Parker, A. Makriyannis, J. D. Salamone, The cannabinoid CB1 antagonist AM 251 produces food avoidance and behaviors associated with nausea but does not impair feeding efficiency in rats Psychopharmacology. ,vol. 180, pp. 286- 293 ,(2005) , 10.1007/S00213-005-2171-0
Beat Lutz, Endocannabinoid signals in the control of emotion Current Opinion in Pharmacology. ,vol. 9, pp. 46- 52 ,(2009) , 10.1016/J.COPH.2008.12.001
Sachin Patel, Cecilia J. Hillard, Pharmacological evaluation of cannabinoid receptor ligands in a mouse model of anxiety: further evidence for an anxiolytic role for endogenous cannabinoid signaling. Journal of Pharmacology and Experimental Therapeutics. ,vol. 318, pp. 304- 311 ,(2006) , 10.1124/JPET.106.101287
Antonio Waldo Zuardi, Antonio E. Nardi, José Alexandre de Souza Crippa, Alexandre Rafael de Mello Schier, Jaime Eduardo Cecilio Hallak, Natalia Pinho de Oliveira Ribeiro, Adriana Cardoso de Oliveira e Silva, Adriana Cardoso de Oliveira e Silva, Cannabidiol, a Cannabis sativa constituent, as an anxiolytic drug Revista Brasileira de Psiquiatria. ,vol. 34, pp. 104- 110 ,(2012) , 10.1590/S1516-44462012000500008
CL Limebeer, VK Vemuri, H Bedard, ST Lang, KP Ossenkopp, A Makriyannis, LA Parker, Inverse agonism of cannabinoid CB1 receptors potentiates LiCl-induced nausea in the conditioned gaping model in rats British Journal of Pharmacology. ,vol. 161, pp. 336- 349 ,(2010) , 10.1111/J.1476-5381.2010.00885.X