Epidemiology of HIV-associated tuberculosis.

摘要: PURPOSE OF REVIEW: We review literature concerning the epidemiology of HIV-associated tuberculosis (HIV-TB) focusing on articles published between 2007 and 2008. RECENT FINDINGS: An estimated 1.37 million new cases HIV-TB occurred in representing 15% total global burden TB. In addition an 456 000 deaths accounted for 23% HIV/AIDS mortality. Sub-Saharan Africa is worst affected region with 79% disease burden. The epicentre coepidemic lies south continent South alone accounting over one quarter all cases. A critical overlap HIV multidrug-resistant TB epidemics emerging. Although it as yet unclear whether driving a disproportionate increase at population level has nevertheless been potent risk factor institutional outbreaks especially eastern Europe. Increasing data have highlighted among HIV-infected healthcare workers resource-limited settings. However many studies also show major benefits to be derived from antiretroviral therapy high-income low-income countries. SUMMARY: remains challenge health that requires substantial increases resource allocation concerted international action.