Villoglandular Adenocarcinoma of the Uterine Cervix: An Analysis of 12 Clinical Cases

摘要: Summary Background Villoglandular adenocarcinoma (VGA) of the uterine cervix is a relatively rare subtype endocervical adenocarcinomas that often occurs in early reproductive women. Methods Clinical cases were retrospectively collected from cancer registry systems at Mackay Memorial Hospital (Taipei, Taiwan). histories on subjects extracted directly chart review records clinic visits. Results The mean age 12 was 42 years, with 10 and 2 clinically staged as IB1 (10 12) IA2 (2 12), respectively, for period between January 1, 1996, December 31, 2007. Eleven had classical Type III radical hysterectomy or without bilateral salpingo-oophorectomy plus pelvic lymphadenectomy, one received para-aortic lymphadenectomy postoperative adjuvant treatment weekly cisplatin concurrent radiotherapy. Only subject confirmed lymph nodes metastases. Nine pure histologic type others mixed VGA. recurrence but still alive. Most long-term survivors (greater than 5 years) 12). Conclusion In conclusion, this study confirms young VGA reemphasizes difficulties diagnosis Because current management strategy renders good tumor control early-stage VGA, we would suggest similar should be considered elder category cervical malignancy. Our experience shows primary (International Federation Gynecology Obstetrics Stages to IIA1) MMH. We hope our 12-case may contribute clinical decision making disease.