An experimental study of micromilling parameters to manufacture microchannels on a PMMA substrate

摘要: Rapidly prototyping a polymer microfluidic device is growing interest in the application fields of disease detection, drug synthesis, and environmental monitoring because benefits miniaturized platforms. Micromilling one micromachining methods it has been commonly used to manufacture devices. The advantages using micromilling for devices include faster fabrication process, lower cost, easier user interface, being capable fabricating complicated structures, which make perfect candidate rapid research idea testing validation. This aim this study understand influence each parameter surface quality, followed by factor analysis determine optimal cutting conditions. parameters included spindle speed, feed rate, depth cut, selection coolant (compressed air/oil coolant), milled quality was measured stylus profilemeter. Polymethyl methacrylate (PMMA) mainstream substrate material microfluidics due its excellent optical property popularity as target substrate. experiment results showed that compressed air can deliver better than oil coolant, smallest roughness achieved 0.13 μm with speed 20,000 rpm, rate 300 mm/min, cut 10 μm. Factor revealed largest impact while minimized micromilled PMMA To further confirm conditions, another 12 reservoirs were conditions average 0.17 stand deviation 0.08