The two NF-κB activation pathways and their role in innate and adaptive immunity

作者: Giuseppina Bonizzi , Michael Karin

DOI: 10.1016/J.IT.2004.03.008

关键词: BiologyTranscription factorCytokineInnate immune systemImmune systemProinflammatory cytokineAcquired immune systemAlternative complement pathwayNFKB1ImmunologyCell biology

摘要: … NF-κB activation was discovered. This pathway, now known as the alternative pathway, is activated … and alternative pathways to NF-κB activation have distinct regulatory functions, one …

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