Ultrastructure of Ewing's Tumour.

作者: C. Povýšil , Z. MatĚjovský

DOI: 10.1007/BF00432653

关键词: BiologyPathologyImmunohistochemistryHistogenesisCytoplasmCell junctionOrganelleAlkaline phosphataseCell membraneUltrastructure

摘要: Tumour tissue surgically excised from 10 patients bearing Ewing's tumour of bones was examined electron microscopically and histoenzymologically. In all cases the composed polygonal cells with cytoplasm poor in organelles but conspicuous aggregates glycogen particles. There were numerous intercellular connections desmosomal type a distinct cell membrane bound positivity for alkaline phosphatase activity. two which there negative reaction phosphatase, lack enzyme activity might have been related to cytotoxic treatment carried out several months immediately before excision used histoenzymological studies. The problem histogenesis remains unresolved although some present findings support haemangiogenic origin tumour.

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