Central Venous Catheter-associated Venous Thromboembolism in Children With Hematologic Malignancy.
作者： Sara-Jane N Onyeama , Sheila J Hanson , Mahua Dasgupta , Kathryn Baker , Pippa M Simpson
DOI: 10.1097/MPH.0000000000001229
关键词: Occlusion 、 Hematologic malignancy 、 Central venous catheter 、 Population study 、 Peripherally inserted central catheter 、 Fisher's exact test 、 Medicine 、 Internal medicine 、 Venous thromboembolism 、 Retrospective cohort study
摘要: In pediatric oncology, the diagnosis of a hematologic malignancy and presence central venous catheter (CVC) have been identified as significant risk factors for development thromboembolism (VTE). There remain little data regarding CVC associated with CVC-related VTE. Using VTE oncology database in quaternary care center, retrospective cohort study was conducted children below 18 years old cancer from November 5, 2012 to April 4, 2016. Patient, factors, occurrence were analyzed identify patient clinically Utilizing χ, Mann-Whitney, Fisher exact tests, compared across yes/no groups. Of 198 patients, 22 cases identified. Eighteen events CVC-associated, occurring 9% population. Peripherally inserted lines older ages The use tissue-plasminogen activator occlusion decreased rates, suggesting protective potential.
sci-hub.se 参考文章(30)
Christoph Male, Peter Chait, Maureen Andrew, Kim Hanna, Jim Julian, Lesley Mitchell, , Central venous line-related thrombosis in children: association with central venous line location and insertion technique. Blood. ,vol. 101, pp. 4273- 4278 ,(2003) , 10.1182/BLOOD-2002-09-2731
Barbara Schmidt, Maureen Andrew, Neonatal thrombosis: report of a prospective Canadian and international registry. Pediatrics. ,vol. 96, pp. 939- 943 ,(1995)
Darryl W. Glaser, Desiree Medeiros, Nancy Rollins, George R. Buchanan, Catheter-related thrombosis in children with cancer ☆ ☆☆ The Journal of Pediatrics. ,vol. 138, pp. 255- 259 ,(2001) , 10.1067/MPD.2001.111272
R. H. White, The Epidemiology of Venous Thromboembolism Circulation. ,vol. 107, ,(2003) , 10.1161/01.CIR.0000078468.11849.66
Alok A. Khorana, Charles W. Francis, Eva Culakova, Nicole M. Kuderer, Gary H. Lyman, Frequency, risk factors, and trends for venous thromboembolism among hospitalized cancer patients. Cancer. ,vol. 110, pp. 2339- 2346 ,(2007) , 10.1002/CNCR.23062
Natalie V. Lipay, Anfisa I. Zmitrovich, Olga V. Aleinikova, Epidemiology of venous thromboembolism in children with malignant diseases: a single-center study of the Belarusian Center for Pediatric Oncology and Hematology. Thrombosis Research. ,vol. 128, pp. 130- 134 ,(2011) , 10.1016/J.THROMRES.2011.03.014
Uma Athale, Anthony Chan, Thromboembolic complications in pediatric hematologic malignancies. Seminars in Thrombosis and Hemostasis. ,vol. 33, pp. 416- 426 ,(2007) , 10.1055/S-2007-976177
Elizabeth A. Chalmers, Epidemiology of venous thromboembolism in neonates and children Thrombosis Research. ,vol. 118, pp. 3- 12 ,(2006) , 10.1016/J.THROMRES.2005.01.010
Dana Piovesan, Chantal Attard, Paul Monagle, Vera Ignjatovic, Epidemiology of venous thrombosis in children with cancer Thrombosis and Haemostasis. ,vol. 111, pp. 1015- 1021 ,(2014) , 10.1160/TH13-10-0827
Janna M. Journeycake, George R. Buchanan, Thrombotic complications of central venous catheters in children Current Opinion in Hematology. ,vol. 10, pp. 369- 374 ,(2003) , 10.1097/00062752-200309000-00008