Growth Hormone and Prader-Willi Syndrome
作者： Aaron L. Carrel , Phillip D. K. Lee , Harriette R. Mogul
DOI: 10.1007/978-0-387-33536-0_7
关键词: Bioinformatics 、 Gh treatment 、 Pathophysiology 、 Endocrine system 、 Growth hormone treatment 、 Metabolic aspects 、 Medicine 、 Growth hormone
摘要: In the previous edition of this textbook, various lines evidence for occurrence a defi ciency in growth hormone (GH) axis were reviewed as one several sections chapter entitled “Endocrine and Metabolic Aspects Prader-Willi Syndrome.” At that time, it was suggested GH therapy may have benefi cial effects on body composition individuals with PWS. Over succeeding decade, number scientifi c investigations provided nitive support these suggestions. 2000, biosynthetic became fi rst and, to date, only medication receive regulatory approval treatment children addition, appears also potential utility adults This presents comprehensive review relevant physiology pathophysiology system effi cacy safety
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