Biological Inactivation of 5-oxo-6,8,11,14-Eicosatetraenoic Acid by Human Platelets

作者: William S. Powell , Sylvie Gravel , Subhash P. Khanapure , Joshua Rokach

DOI: 10.1182/BLOOD.V93.3.1086

关键词: BiochemistryEicosanoidCalciumMetabolismPlateletChemistryDehydrogenaseBiosynthesisEnzymeEicosatetraenoic acid

摘要: … 5-oxo-ETE by platelets stimulated with thrombin or A23187. In contrast, unstimulated platelets converted 5-oxo-ETE … We conclude that platelets can biologically inactivate 5-oxo-ETE. …

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