Coronary artery blood how: Physiologic and pathophysiologic regulation

摘要: Acute myocardial ischemia, which results from a significant imbalance between oxygen demands and supply, occurs in as many six million persons with atherosclerotic coronary artery disease the United States. Accordingly, clear understanding of physiologic pathophysiologic factors that influence blood flow is important to clinician provides basis for judicious use medications treatment patients disease. This review discusses endothelial, metabolic, myogenic, neurohumoral mechanisms regulation interaction different flow. The importance nitric oxide emphasized. We also discuss common clinical problems hyperlipidemia atherosclerosis, spasm, systemic arterial hypertension result endothelial dysfunction, impaired production increased inactivation oxide, impairment regulation. information clinicians because more than forty people States have or hypertensive heart therefore are at risk complications due