A cationic surfactant-concentration dependent binding of a guest molecule with the nanotubes of β-cyclodextrin and its release from the nanotubular cavities

摘要: The effect of concentration a cationic surfactant, cetylpyridinium chloride (CPyCl), on the inclusion complex between β-cyclodextrin (β-CD) and guest molecule, trans-2-[4-(dimethylamino)styryl]benzothiazole (DMASBT), has been studied by exploiting twisted intramolecular charge transfer (TICT) fluorescence properties latter. steady-state fluorescence, anisotropy, time-resolved DMASBT dynamic light scattering (DLS) methods have used to monitor different phases binding CPyCl with β-CD–DMASBT system. At chosen β-CD (8.0 mM), molecules in presence 5.0 μM exist as extended nanotubes forming rod-like suprastructures along simple adducts single nanotubes. very low (<0.7 it partially binds all forms complexes. Above 0.7 mM, effectively system β-CD–DMASBT–CPyCl complex. premicellar aggregation starts at ∼10.0 mM CPyCl, while micellization occurs ∼20.0 which is suggested be apparent critical micellar (CMC*) CPyCl. CMC*, replace almost from cavities released then get solubilized micelles This phenomenon suggests that present can explored for development drug-delivery hydrodynamic radii various components solution determined DLS method.