Role of Asymptomatic Carriers in Long-Term Care Facility Clostridioides (Clostridium) difficile Transmission

作者: Ravina Kullar , Ellie J. C. Goldstein

DOI: 10.1007/978-3-030-29772-5_3

关键词: Infection controlLong-term careAsymptomaticIsolation (health care)MedicineTransmission (medicine)Clostridium difficileIntensive care medicineDiarrheaAsymptomatic carrier

摘要: Clostridioides (Clostridium) difficile remains the leading cause of healthcare-associated diarrhea, with ~30,000 deaths due to infection (CDI) annually in United States. Patients long-term care facilities (LTCFs), particularly, carry an increased susceptibility acquiring CDI and up a 51% rate asymptomatic colonization. Knowing patient’s carrier status at admission could benefit LTCF, positive cases, providing optimal prevention procedures would curtail spread pathogen reduce number subsequent cases. We recommend risk-adapted algorithm carriers LTCFs, including, upon admission, screening high-risk patients prior episodes CDI, previous hospitalization, antibiotic treatment. Of note, LTCFs are residence many patients, need for isolation must be balanced home-like environment. Further studies evaluating clinical consequences C. colonization warranted.

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