Neurocognitive Function Following Therapy for Low-Grade Gliomas.

作者: Mary Frances McAleer , Paul D. Brown

DOI: 10.1016/J.SEMRADONC.2015.02.005

关键词: Young adultPrimary Brain NeoplasmsNeurocognitiveFavorable prognosisChemotherapyOncologyQuality of lifeRadiation therapyPsychiatryInternal medicinePatient populationMedicine

摘要: Low-grade gliomas (LGGs) are a heterogenous group of primary brain neoplasms that most commonly occur in children and young adults, characterized by slow, indolent course overall favorable prognosis. Standard therapies used to treat LGGs have included surgical resection, radiotherapy, chemotherapy, or combination thereof. Given the anticipated long survival typical age patients with LGG, long-term sequelae therapy require special attention, especially as they affect neurocognitive function quality life. We review complex interplay baseline treatment-related factors perturb neurocognition well effect each treatment modality on altering outcomes this patient population.

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