作者: Norie Sugitani , Robert M. Sivley , Kelly E. Perry , John A. Capra , Walter J. Chazin
DOI: 10.1016/J.DNAREP.2016.05.018
关键词: Genetics 、 Biology 、 DNA repair 、 Xeroderma pigmentosum 、 Nucleotide excision repair 、 Genome 、 Proliferating cell nuclear antigen 、 NLS 、 Transcription factor II H 、 DNA
摘要: Nucleotide excision repair (NER) is essential for removing many types of DNA lesions from the genome, yet mechanisms NER in humans remain poorly understood. This review summarizes our current understanding structure, biochemistry, interaction partners, mechanisms, and disease-associated mutations one critical proteins, XPA.