Factors associated with mother‐to‐child transmission of the human immunodeficiency virus in Pernambuco, Brazil, 2000–2009

摘要: Objective To identify risk factors associated with mother-to-child transmission of HIV in the Brazilian state Pernambuco. Methods Retrospective cohort study 1200 HIV-exposed children born Pernambuco, registered up to age 2 months a public programme prevent vertical transmission. Univariate and multivariate logistic regression analyses were conducted for maternal peripartum characteristics prophylactic interventions, HIV. Results The rate was 9.16% (95% CI: 7.4–10.9). The following independently transmission: non-use antiretroviral during pregnancy (OR: 7.8; 95% 4.1–15); vaginal delivery 2.02; 1.2–3.4); prematurity 2.5; 1.3–4.7); breastfeeding 2.6; 1.4–4.6). Conclusions This is unacceptably high, as interventions such therapy infant feeding formula are free charge. Absence main factor. Therefore, early identification exposed mothers initiating challenges controlling transmission. Objectif Identifier les facteurs de risque associes la mere-enfant du VIH dans l’etat bresilien Pernambuco. Methodes Etude retrospective cohorte enfants exposes au VIH, nes Pernambuco et enregistres jusqu’a l’âge deux mois un pour prevention verticale. Des logistique univariee multivariee ont ete effectuees caracteristiques maternelles peri-partum prophylactiques, afin d'identifier VIH. Resultats Le taux etait 9,16% (IC95%: 07,04 10,09). Les suivants etaient independamment non-utilisation des antiretroviraux pendant grossesse 7,8; IC95%: 4,1 15), l'accouchement par voie vaginale 2,02; 1,2–3,4), prematurite 2,5; 1,3 4,7), l'allaitement maternel 2,6; 1,4 4,6). Conclusions Ce est trop eleve, car prophylactiques telles que therapie antiretrovirale l'alimentation nourrisson biberon sont gratuits. L'absence traitement le principal facteur risque. Par consequent l'identification precoce meres exposees l'initiation principaux defis controler transmission. Objetivo Identificar los factores riesgo asociados con transmision madre-hijo del en el estado Brasilero Pernambuco. Metodos Estudio retrospectivo cohortes 1,200 ninos expuestos al y nacidos registrados hasta una edad dos meses dentro programa publico para prevenir vertical. Se realizaron analisis regresion logistica univariada multivarida las caracteristicas maternas periparto e intervenciones profilacticas, fin identificar VIH. Resultados La tasa era (IC 95%: Los siguientes estaban independientemente transmision: no utilizar antirretrovirales durante embarazo IC parto prematuridad amamantar 1.4–4.6). Conclusiones Esta es inaceptablemente alta, puesto profilacticas tales como terapia antirretroviral o leche alimentar recien nacido son gratuitas. La ausencia factor riesgo. Por lo tanto identificacion temprana madres expuestas inicio profilaxis principales retos controlar transmision.