Maternal Low Quality Protein Diet Alters Plasma Amino Acid Concentrations of Weaning Rats

作者: Arzu Kabasakal Cetin , Halil Dasgin , Atila Gülec , İlyas Onbasilar , Asli Akyol

DOI: 10.3390/NU7125508

关键词: GlutamineAmino acidOffspringMethionineWeaningLow-protein dietEndocrinologyCaseinLactationInternal medicineBiology

摘要: Several studies have indicated the influence of a maternal low protein diet on fetus. However, effect quality fetal growth and development is largely unknown. Wistar rats (11 weeks old) were mated maintained either chow with 20% casein (n = 6) as control group (C), or wheat gluten 7) experimental (WG) through gestation lactation. Maternal body weights similar in both groups throughout study. Birth not influenced by offspring during lactation between groups. Offspring's plasma amino acid profiles showed that methionine, glutamine lysine significantly lower aspartic acid, ornithine glycine-proline higher WG. Plant based comprises an important part intake developing countries. It well-known these diets can be inadequate terms essential acids. The current study shows differential effects offspring's Future will examine further aspects development.

参考文章(57)
A Palou, L Arola, M Alemany, Plasma amino acid concentrations in pregnant rats and in 21-day foetuses. Biochemical Journal. ,vol. 166, pp. 49- 55 ,(1977) , 10.1042/BJ1660049
Yimin Jia, Guichao Gao, Haogang Song, Demin Cai, Xiaojing Yang, Ruqian Zhao, Low-protein diet fed to crossbred sows during pregnancy and lactation enhances myostatin gene expression through epigenetic regulation in skeletal muscle of weaning piglets European Journal of Nutrition. ,vol. 55, pp. 1307- 1314 ,(2016) , 10.1007/S00394-015-0949-3
Fuller W. Bazer, Gregory A. Johnson, G. Wu, Amino acids and conceptus development during the peri-implantation period of pregnancy. Advances in Experimental Medicine and Biology. ,vol. 843, pp. 23- 52 ,(2015) , 10.1007/978-1-4939-2480-6_2
Vernon R Young, J Sergio Marchini, Joaquin Cortiella, None, Assessment of protein nutritional status. Journal of Nutrition. ,vol. 120, pp. 1496- 1502 ,(1990) , 10.1093/JN/120.SUPPL_11.1496
Hugh J. Freeman, Young S. Kim, Marvin H. Sleisenger, Protein digestion and absorption in man The American Journal of Medicine. ,vol. 67, pp. 1030- 1036 ,(1979) , 10.1016/0002-9343(79)90645-4
Robert A. Burns, Mary H. LeFaivre, John. A. Milner, Effects of Dietary Protein Quantity and Quality on the Growth of Dogs and Rats Journal of Nutrition. ,vol. 112, pp. 1843- 1853 ,(1982) , 10.1093/JN/112.10.1843
G. Richard Jansen, Robert Binard, John B. Longenecker, Protein quality and quantity influence free amino acid levels in the brain and serum of rats during lactation. Journal of Nutrition. ,vol. 121, pp. 1187- 1194 ,(1991) , 10.1093/JN/121.8.1187
G. Richard Jansen, Mary B. Schibly, Marc Masor, David A. Sampson, John B. Longenecker, Free amino acid levels during lactation in rats: effects of protein quality and protein quantity Journal of Nutrition. ,vol. 116, pp. 376- 387 ,(1986) , 10.1093/JN/116.3.376
Lewis Menaker, Juan M. Navia, Appetite Regulation in the Rat Under Various Physiological Conditions: The Role of Dietary Protein and Calories The Journal of Nutrition. ,vol. 103, pp. 347- 352 ,(1973) , 10.1093/JN/103.3.347