Malaria : parasite biology, pathogenesis, and protection

摘要: A Brief History of Malaria and Discovery the Parasite's Life Cycle The Current Global Situation Gametocytes Sexual Development Sporogonic in Mosquito Engineering Resistance to Parasite Mosquitoes Invasion Vertebrate Cells: Hepatocytes Erythrocytes Ultrastructure Asexual Stages Carbohydrate Metabolism Hemoglobin Processing Amino Acids, Heme Iron Malarial Lipids Purine Pyrimidine DNA Plasmodium rRNA Genes Membrane Transport Malaria-Infected Erythrocyte Genetic Structure Populations Genome Research: Status Promise Extrachromosomal DNA: Mitochondrion Plastid Evolutionary Relationships Human Parasites Introduction Modes Action Mechanisms Anitmalarials Molecular Basis Sulfones, Sulfamides, Dihydrofolate Reductase Inhibitors Chloroquine: Actions Activity Chloroquine Analogs From Quinine Qinghaosu: Historical Perspectives Mitochondrial Physiology as a Target for Atovaquone Other Antimalarials Pathophysiology Rosetting Animal Models: Rodents Primates Host Factors Acquired Immunity Blood Sporozoites Liver Using DNA-Based Vaccine Technology Project Overcome Obstacles Development.