Histologic characteristics of cells cultured from rat placental tissue

作者: F.G. Ferguson , J. Palm

DOI: 10.1016/0002-9378(76)90103-4

关键词: Cell typeCytotrophoblastsImmune systemRound cellsPathologyBiologyPlacental tissueAmitosisMultinucleateGiant cellObstetrics and gynaecology

摘要: Abstract Laboratory animals, especially rats, have provided a comparative model for extensive research on maternal-fetal relationships. To identify individual placental cells subsequent immunologic analysis, cultures of rat placentas were studied. Five cell types observed, including: two histologically distinct giant cells, mononucleate and multinucleate, apparently formed by amitosis fusion, respectively; small round cells; polygonal probably cytotrophoblasts; fibroblasts. Of particular interest are the which phagocytic morphologically similar to macrophages, known be important in immune response.

参考文章(13)
William L. Epstein, Martin M. Black, Formation of multinucleate giant cells in organized epitheloid cell granulomas. American Journal of Pathology. ,vol. 74, pp. 263- 274 ,(1974)
Zeev Koren, S.J. Behrman, Organ culture of pure mouse trophoblast American Journal of Obstetrics and Gynecology. ,vol. 100, pp. 576- 581 ,(1968) , 10.1016/S0002-9378(15)33496-7
John C. Garancis, Ronald A. Pattillo, Robert O. Hussa, John Schultz, Richard F. Mattingly, Electron microscopic and biochemical patterns of the normal and malignant trophoblast American Journal of Obstetrics and Gynecology. ,vol. 108, pp. 1257- 1268 ,(1970) , 10.1016/0002-9378(70)90102-X
Michael Schlesinger, Zeev Koren, Mouse Trophoblastic Cells in Tissue Culture Fertility and Sterility. ,vol. 18, pp. 95- 101 ,(1967) , 10.1016/S0015-0282(16)36190-8
Michael I. Sherman, Peter W. Barlow, The biochemistry of differentiation of mouse trophoblast: studies on polyploidy Development. ,vol. 27, pp. 447- 465 ,(1972) , 10.1242/DEV.27.2.447
T. GILLMAN, L. J. WRIGHT, Probable in vivo origin of multi-nucleated giant cells from circulating mononuclears. Nature. ,vol. 209, pp. 263- 265 ,(1966) , 10.1038/209263A0
Frank M. Saccoman, Charles F. Morgan, Lemen J. Wells, Radioautographic studies of DNA synthesis in the developing extraembryonic membranes of the mouse The Anatomical Record. ,vol. 158, pp. 197- 205 ,(1967) , 10.1002/AR.1091580209
M. I. SHERMAN, ANNE MCLAREN, P. M. B. WALKER, Mechanism of accumulation of DNA in giant cells of mouse trophoblast. Nature. ,vol. 238, pp. 175- 176 ,(1972) , 10.1038/NEWBIO238175A0
Tien-Wen Tao, Arthur T. Hertig, VIABILITY AND DIFFERENTIATION OF HUMAN TROPHOBLAST IN ORGAN CULTURE. American Journal of Anatomy. ,vol. 116, pp. 315- 327 ,(1965) , 10.1002/AJA.1001160116