H2O2 is required for UVB-induced EGF receptor and downstream signaling pathway activation.

作者: Timothy O’Brien , Mark R Pittelkow , Dominik Peus , Alexander Meves , Remus A Vasa

DOI: 10.1016/S0891-5849(99)00198-7

关键词: Signal transductionMitogen-activated protein kinaseMAPK/ERK pathwaySecond messenger systemAutophosphorylationp38 mitogen-activated protein kinasesEpidermal growth factor receptorPhosphorylationCell biologyBiology

摘要: … 2 (ERK1/2), and p38 signaling pathways via reactive oxygen species. Here we demonstrate that … that is required for EGFR and dependent downstream signaling pathways activation. …

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