Sperm associated antigen 5 (SPAG5) as a predictor and monitor for response and distant relapse risk (DRR) to endocrine (ET) and chemo-therapies (CT) in oestrogen receptor positive (ER+) breast cancer (BC).

作者: Tarek Mohamed Ahmed Abdel-Fatah , Graham Ball , Amy McCart Reid , Peter Simpson , Sunil R Lakhani

DOI: 10.1200/JCO.2018.36.15_SUPPL.1066

关键词: Copy number aberrationOestrogen receptorMessenger RNADistant relapseEr breast cancerMedicineSperm associated antigen 5Proliferation MarkerEndocrine systemCancer research

摘要: 1066Background: SPAG5 is an ultimate proliferation marker and important driver that commonly amplified in “luminal B” BC. Methods: copy number aberrations (CNAs), mRNA protein expressi...

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