In Vitro Culture Techniques

作者: W. H. G. Richards

DOI: 10.1007/978-3-642-69251-2_3

关键词: BioinformaticsAvian malariaPlasmodium bergheiBiologyDrug resistanceMechanism (biology)DiseaseMalariaPlasmodium knowlesiPlasmodium falciparum

摘要: The control of malaria by chemotherapy, the use pesticides, and public health measures has been curtailed increasing spread drug resistance parasite, especially Plasmodium falciparum, while increased tolerance mosquito vectors to older insecticides exacerbated global problem facilitating return infection areas recently freed from disease. search for new chemotherapeutic agents investigations aimed at a better understanding existing antimalarials is an expensive time-consuming task, usually only undertaken in more sophisticated laboratories. successful vitro cultivation blood, tissue sporogonic stages parasite could quickly easily provide means examine compounds against target species, or acceptable experimental model. It should allow mechanism invasion, biochemistry, physiology, resistance, immunology.

参考文章(74)
R Carter, L H Miller, Evidence for environmental modulation of gametocytogenesis in Plasmodium falciparum in continuous culture. Bulletin of The World Health Organization. pp. 37- 52 ,(1979)
Eric G. Ball, Ralph W. McKee, Christian B. Anfinsen, Walter O. Cruz, Quentin M. Geiman, STUDIES ON MALARIAL PARASITES: IX. CHEMICAL AND METABOLIC CHANGES DURING GROWTH AND MULTIPLICATION IN VIVO AND IN VITRO Journal of Biological Chemistry. ,vol. 175, pp. 547- 571 ,(1948) , 10.1016/S0021-9258(18)57175-1
B. D. Gomperts, Metabolic changes in human red cells during incubation of whole blood in vitro. Biochemical Journal. ,vol. 102, pp. 782- 790 ,(1967) , 10.1042/BJ1020782
Wasim A. Siddiqui, Quentin M. Geiman, Jerome V. Schnell, In Vitro Cultivation of Plasmodium falciparum American Journal of Tropical Medicine and Hygiene. ,vol. 19, pp. 586- 591 ,(1970) , 10.4269/AJTMH.1970.19.586
L. W. Scheibel, R. E. Desjardins, W. H. Wernsdorfer, R. Sinden, J. D. Haynes, W. H. G. Richards, New developments in malaria chemotherapy using in vitro cultures. Current chemotherapy and infectious disease. Proceedings of the 11th International Congress of Chemotherapy, and the 19th Interscience Conference on Antimicrobial Agents and Chemotherapy, Boston, Massachusetts, 1-5 October 1979. Volume 1.. pp. 10- 13 ,(1980)
W. Trager, Cultivation of erythrocytic stages of malaria. UNDP/World Bank/WHO Special Programme for Research and Training in Tropical Diseases. : The in vitro cultivation of the pathogens of tropical diseases.: [Proceedings of the Workshop held in Nairobi, Kenya, 4-9 February 1979].. pp. 3- 13 ,(1980)
G PASVOL, Fetal haemoglobin and malaria. The Lancet. ,vol. 307, pp. 1269- 1272 ,(1976) , 10.1016/S0140-6736(76)91738-4
H. Van den Bossche, Biochemistry of parasites and host-parasite relationships. Biochemistry of parasites and host-parasite relationships.. ,(1976)
I.M. Tonkin, F. Hawking, Growth of protozoa in tissue culture Transactions of the Royal Society of Tropical Medicine and Hygiene. ,vol. 41, pp. 407- 414 ,(1947) , 10.1016/S0035-9203(47)90159-4
David A. Foley, Janis Kennard, Jerome P. Vanderberg, Plasmodium berghei: infective exoerythrocytic schizonts in primary monolayer cultures of rat liver cells. Experimental Parasitology. ,vol. 46, pp. 166- 178 ,(1978) , 10.1016/0014-4894(78)90129-7