作者: W. H. G. Richards
DOI: 10.1007/978-3-642-69251-2_3
关键词: Bioinformatics 、 Avian malaria 、 Plasmodium berghei 、 Biology 、 Drug resistance 、 Mechanism (biology) 、 Disease 、 Malaria 、 Plasmodium knowlesi 、 Plasmodium falciparum
摘要: The control of malaria by chemotherapy, the use pesticides, and public health measures has been curtailed increasing spread drug resistance parasite, especially Plasmodium falciparum, while increased tolerance mosquito vectors to older insecticides exacerbated global problem facilitating return infection areas recently freed from disease. search for new chemotherapeutic agents investigations aimed at a better understanding existing antimalarials is an expensive time-consuming task, usually only undertaken in more sophisticated laboratories. successful vitro cultivation blood, tissue sporogonic stages parasite could quickly easily provide means examine compounds against target species, or acceptable experimental model. It should allow mechanism invasion, biochemistry, physiology, resistance, immunology.