The interrelationships between chronic diarrhoea and malnutrition

摘要: Publisher Summary This chapter describes the interrelationships between chronic diarrhea and malnutrition. The close association in infants young children malnutrition is well recognized, syndrome a dominating cause of morbidity mortality Third World. resident microbial population itself exerts powerful force to repel invaders. mechanisms are again complex include substrate competition, maintenance [H+] redox potential, production short-chain fatty acids, synthesis colicins. contamination small bowel clear. causes probably multifactorial, with diminished gastric acid environmental being as important impaired immunity. Direct alteration mucosal function by bacteria can result from: attachment toxin only, no structural limited damage apical membrane, penetration or destruction mucosa organisms such Shigella. relationships infection synergistic, each factor adversely affects other.