Mechanism for human papillomavirus transmission at birth.
作者： Thomas V Sedlacek , Steven Lindheim , Catherine Eder , Lisa Hasty , Mark Woodland
DOI: 10.1016/0002-9378(89)90232-9
关键词: In utero 、 Papillomaviridae 、 Nasopharyngeal aspirate 、 Nucleic acid 、 Biology 、 Virology 、 Oral pharyngeal 、 Southern blot 、 Amniotic fluid 、 Virus
摘要: We attempted to investigate mechanisms, in addition sexual contact, by which human papillomaviruses associated with anogenital tract lesions could be transmitted. Samples of exfoliated cervical cells were obtained from 45 pregnant women and assayed Southern blot hybridization analysis for the presence papillomavirus nucleic acids. Twenty-five had positive deoxyribonucleic acid. A neonatal nasopharyngeal aspirate was at term analyzed documented acid oral pharyngeal cavity neonates 15 samples analyzed. Amniotic fluid 13 patients when their membranes artificially ruptured. These acid; two amniotic contained The detection is indicative a perinatal mechanism viral transmission. may suggest an utero However, problems encountered collecting preclude us definitive interpretation these data.
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