Neurodevelopmental Outcomes of Extremely Low Birth Weight Infants Ventilated With Continuous Positive Airway Pressure vs. Mechanical Ventilation

摘要: To compare continuous positive airway pressure (CPAP) vs. traditional mechanical ventilation (MV) at 24 h of age as predictors neurodevelopmental (ND) outcomes in extremely low birth weight (ELBW) infants 18–22 months corrected gestational (CGA). Infants ≤1000 g born from January 2000 through December 2006 two hospitals the Cincinnati site National Institute Child Health and Human Development Neonatal Research Network were evaluated comparing CPAP (n = 198) MV (n = 109). Primary included Bayley Score Infant Version II (BSID-II), presence deafness, blindness, cerebral palsy, bronchopulmonary dysplasia death. Ventilatory groups similar gender, rates preterm prolonged rupture membranes, antepartum hemorrhage, use antenatal antibiotics, steroids, tocolytics. receiving weighed more, older, more likely to be non-Caucasian a singleton pregnancy. had better BSID-II scores, lower BPD After adjusting for acuity differences, ventilatory strategy independently predicts long-term outcome ELBW infants.