Antibacterial efficacy of polymer containing nanoparticles in comparison with sodium hypochlorite in infected root canals.

摘要: AIM The aim of the present study was to compare antibacterial properties PLGA polymer containing ZnO, Ag and ZnO/Ag nanoparticles with those 2.5% NaOCl in root canals contaminated Enterococcus faecalis. METHODS A total 100 maxillary central incisors were selected. After crowns removed achieve 12-mm-length roots, prepared RaCe rotary system. samples sterilized; then 200 µL E. faecalis suspension (ATCC 29212) placed each canal. divided into 5 groups based on agent used. Group 1 served as control group. In group 2 ZnO nanoparticles, 3 solution 4 5, 24 hours, a using dentin chips from canal agar plates, followed by colony-forming units (CFU) count determination. Means ± standard deviations calculated Kruskal-Wallis test used evaluate different irrigation agents. Mann-Whitney U for two-by-two comparisons groups, level significance being set at 0.05. RESULTS maximum minimum CFU counts observed respectively. There significant differences between after application solutions (P<0.05). Two-by-two showed all (P<0.05), except (P=0.7). CONCLUSION Sodium hypochlorite more effective than copolymer tested nanoparticles; exhibited highest activity.