Rectal cancer with synchronous liver metastases: leave it all in? When (not) to resect the primary?

摘要: Rectal cancer with synchronous distant metastases is challenging the choice of optimal treatment. Today, it unknown if and when primary tumor should or not be resected. The current literature was reviewed. Data on safety a chemotherapy approach are reported. These publications indicate that at least in selected situations without severe symptoms complications resulting from primary, rectum can left situ major risks for patient. However, retrospective analyses randomized controlled trials potential prognostic advantage patients having reason this observation largely requires further investigation. Due to lack data prospective illuminating situation rectal due rapid changes evolving field systemic treatment metastatic colorectal cancer, no clear conclusions drawn stage. But practical algorithm may reflect European patterns presented article.