Fine‐needle biopsy of pediatric lesions: A three‐year study in an outpatient biopsy clinic

作者: Carol C. Eisenhut , Douglas E. King , William A. Nelson , Lizabeth C. Olson , Roger W. Wall

DOI: 10.1002/(SICI)1097-0339(199602)14:1<43::AID-DC9>3.0.CO;2-W

关键词: Fine needle biopsyAcinic cell carcinomaBiopsySurgeryThyroidPilomatrixomaSoft tissuePopulationMedicineEl Niño

摘要: Diagnostic Cytology Laboratory, Inc., has an outpatient Fine Needle Biopsy Clinic, which evaluated 7,487 fine-needle biopsies (FNB) from January 1989 to February 1992. Two hundred eighty-eight (3.8%) of these specimens were collected patients 19 years old or younger and this represents the largest study population in scientific literature. The majority obtained palpable masses head neck region [lymph nodes (58.3%), thyroid (7.6%), salivary gland (5.2%)] while a smaller number miscellaneous soft tissue (18.8%) breast (10.1%). Thirteen (4.5%) (from 12 patients) diagnosed as malignant by FNB 275 (95.5%) (264 benign FNB. This benign:malignant ratio (22:1) is significantly higher than been reported tertiary care institutions reflection difference population. nine 276 (75.7%) had adequate follow-up, including 137 (49.6%) followed observation, 48 (17.4%) surgical biopsy, 24 (8.7%) some other modality: imaging studies, flow cytometry, treatment. There was single false positive diagnosis (a pilomatrixoma) one (1) negative interpretation cystic acinic cell carcinoma) resulting diagnostic sensitivity 92.3% specificity 99.6%. predictive value 92.3%, 99.6%, test efficiency 99.3%. utility, cost-effectiveness uniqueness clinic discussed.

参考文章(16)
K Bottles, T R Miller, M B Cohen, A R Ablin, The use of fine-needle aspiration biopsy in children. Western Journal of Medicine. ,vol. 150, pp. 665- 667 ,(1989)
Paul E. Wakely, Merits of fine-needle aspiration biopsy in children: Head and neck Diagnostic Cytopathology. ,vol. 8, pp. 299- 301 ,(1992) , 10.1002/DC.2840080321
Robert T. Schaller, Joanne F. Schaller, Christie Buschmann, Nancy Kiviat, The usefulness of percutaneous fine-needle aspiration biopsy in infants and children Journal of Pediatric Surgery. ,vol. 18, pp. 398- 405 ,(1983) , 10.1016/S0022-3468(83)80189-4
Paul E. Wakely, Thomas F. Kardos, William J. Frable, Application of fine needle aspiration biopsy to pediatrics Human Pathology. ,vol. 19, pp. 1383- 1386 ,(1988) , 10.1016/S0046-8177(88)80230-2
Lydia Pleotis Howell, Liisa A. Russell, P. Holbrook Howard, Raymond L. Teplitz, The cytology of pediatric masses: A differential diagnostic approach Diagnostic Cytopathology. ,vol. 8, pp. 107- 115 ,(1992) , 10.1002/DC.2840080204
David L. Mobley, Paul E. Wakely, Mary Ann Smith Frable, Fine-needle aspiration biopsy: application to pediatric head and neck masses. Laryngoscope. ,vol. 101, pp. 469- 472 ,(1991) , 10.1288/00005537-199105000-00004
A. Rajwanshi, K. L. N. Rao, R. K. Marwaha, V. S. Nijhawan, S. K. Gupta, Role of fine-needle aspiration cytology in childhood malignancies. Diagnostic Cytopathology. ,vol. 5, pp. 378- 382 ,(1989) , 10.1002/DC.2840050407
Kusum Verma, Eusum Kapila, Fine needle aspiration cytology in pediatric oncology Indian Journal of Pediatrics. ,vol. 55, pp. 403- 407 ,(1988) , 10.1007/BF02810362
M. J. Diament, P. Stanley, S. Taylor, Percutaneous fine needle biopsy in pediatrics. Pediatric Radiology. ,vol. 15, pp. 409- 411 ,(1985) , 10.1007/BF02388363
Barbara E. McGahey, Ann T. Moriarty, William A. Nelson, Meredith T. Hull, Fine-needle aspiration biopsy of small round blue cell tumors of childhood. Cancer. ,vol. 69, pp. 1067- 1073 ,(1992) , 10.1002/1097-0142(19920215)69:4<1067::AID-CNCR2820690439>3.0.CO;2-O