作者: Carol C. Eisenhut , Douglas E. King , William A. Nelson , Lizabeth C. Olson , Roger W. Wall
DOI: 10.1002/(SICI)1097-0339(199602)14:1<43::AID-DC9>3.0.CO;2-W
关键词: Fine needle biopsy 、 Acinic cell carcinoma 、 Biopsy 、 Surgery 、 Thyroid 、 Pilomatrixoma 、 Soft tissue 、 Population 、 Medicine 、 El Niño
摘要: Diagnostic Cytology Laboratory, Inc., has an outpatient Fine Needle Biopsy Clinic, which evaluated 7,487 fine-needle biopsies (FNB) from January 1989 to February 1992. Two hundred eighty-eight (3.8%) of these specimens were collected patients 19 years old or younger and this represents the largest study population in scientific literature. The majority obtained palpable masses head neck region [lymph nodes (58.3%), thyroid (7.6%), salivary gland (5.2%)] while a smaller number miscellaneous soft tissue (18.8%) breast (10.1%). Thirteen (4.5%) (from 12 patients) diagnosed as malignant by FNB 275 (95.5%) (264 benign FNB. This benign:malignant ratio (22:1) is significantly higher than been reported tertiary care institutions reflection difference population. nine 276 (75.7%) had adequate follow-up, including 137 (49.6%) followed observation, 48 (17.4%) surgical biopsy, 24 (8.7%) some other modality: imaging studies, flow cytometry, treatment. There was single false positive diagnosis (a pilomatrixoma) one (1) negative interpretation cystic acinic cell carcinoma) resulting diagnostic sensitivity 92.3% specificity 99.6%. predictive value 92.3%, 99.6%, test efficiency 99.3%. utility, cost-effectiveness uniqueness clinic discussed.