Nitric oxide inhibits myocardial apoptosis by preventing caspase-3 activity via S-nitrosylation.
作者： Y MAEJIMA , S ADACHI , K MORIKAWA , H ITO , M ISOBE
DOI: 10.1016/J.YJMCC.2004.10.012
关键词: Molecular biology 、 Phosphorylation 、 Immunoprecipitation 、 Snap 、 S-Nitrosylation 、 Nitric oxide 、 Chemistry 、 Caspase 、 Apoptosis 、 Caspase 3
摘要: … Immunoblot analysis showed that accumulation of the cleaved caspase-3 protein, an active form that induces apoptosis was inhibited significantly by SNAP. To elucidate nitrosothiol …
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