Influence of Local Tumor Control on Distant Metastases and Cancer Related Mortality After External Beam Radiotherapy for Prostate Cancer

作者: Michael J. Zelefsky , Victor E. Reuter , Zvi Fuks , Peter Scardino , Alison Shippy

DOI: 10.1016/J.JURO.2007.11.063

关键词: RadiologyProstate cancerSurgeryCancerProstate biopsyProstateProstate-specific antigenRadiation therapyMetastasisMedicineExternal beam radiotherapyUrology

摘要: Purpose: We report local control outcomes, as assessed by posttreatment biopsies in patients who underwent 3-dimensional conformal radiotherapy for clinically localized prostate cancer. In addition, we the influence of tumor on long-term distant metastases and cause specific survival outcomes.Materials Methods: Posttreatment were performed 339 The histological outcome biopsy was classified positive—prostatic adenocarcinoma without typical radiation induced changes or negative—no evidence carcinoma severe treatment effect. Median followup this group 10 years after completion 6.25 biopsy.Results: Overall outcomes these positive 32%, effect 21% negative 47%. A higher dose intermediate high risk subgr...

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