Population growth of human Y chromosomes: a study of Y chromosome microsatellites.

作者: J. K. Pritchard , M. T. Seielstad , A. Perez-Lezaun , M. W. Feldman

DOI: 10.1093/OXFORDJOURNALS.MOLBEV.A026091

关键词: Chromosome 17 (human)PopulationChromosome 22Y linkageChromosome 21Y chromosomeBiologyMost recent common ancestorMutation (genetic algorithm)Evolutionary biology

摘要: We use variation at a set of eight human Y chromosome microsatellite loci to investigate the demographic history chromosome. Instead assuming population constant size, as in most previous work on chromosome, we consider model which permits period recent growth. show that for populations our sample this fits data far better than with no estimate parameters each and also time common ancestor. Since there is some uncertainty about details mutation process, several plausible schemes variance size simultaneously interest. Our finding ancestor (probably last 120,000 years), coupled strong signal expansion all populations, suggests either from small ancestral population, or natural selection acting

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