Brain Activity Measured by Functional Magnetic Resonance Imaging is Related to Patient Reported Urgency Urinary Incontinence Severity

作者: Stasa D. Tadic , Derek Griffiths , Werner Schaefer , Cathy I. Cheng , Neil M. Resnick

DOI: 10.1016/J.JURO.2009.08.155

关键词: UrologyUrge urinary incontinenceMagnetic resonance imagingUrinary systemUrodynamic testingSurgeryStatistical parametric mappingNeuroimagingUrinary incontinenceMedicineUrinary bladder

摘要: Purpose: We investigated the relationship between experimental neuroimaging and self-reported urinary incontinence measures.Materials Methods: evaluated 14 functionally independent, community dwelling women older than 60 years with moderate to severe urgency incontinence. All underwent detailed clinical assessment (3-day bladder diary, 24-hour pad test quality of life assessment), urodynamic testing functional brain scanning. Brain activity during reported was assessed using a method that combines magnetic resonance imaging simultaneous monitoring repeat filling/emptying cycles. used statistical parametric mapping program SPM2 (http://www.fil.ion.ucl.ac.uk/spm/spm2.html) correlate relevant covariates, including number incontinent episodes, amount urine leakage psychological burden as by Urge Impact Scale questionnaire.Results: Activity in rostral subgenual ...

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