Management of hematologic malignancies in the elderly: 15-year experience at the Aviano Cancer Center, Italy
作者： Vittorina Zagonel , Silvio Monfardini , Umberto Tirelli , Antonino Carbone , Antonio Pinto
DOI: 10.1016/S1040-8428(00)00126-8
关键词: Myelodysplastic syndromes 、 Non-Hodgkin's lymphoma 、 Cancer 、 Multiple myeloma 、 Clinical trial 、 Geriatrics 、 Geriatric oncology 、 Natural history 、 Intensive care medicine 、 Surgery 、 Medicine
摘要: Abstract The optimal management of hemopoietic malignancies in the elderly requires specific strategies targeted at peculiar clinico–biologic features such patients. In time frame spanning from 1983 to 1998, several clinical trials have been performed Aviano Cancer Center, Italy, aimed extending knowledge natural history and evaluating efficacy toxicity different chemotherapy programs specifically devised for older subjects affected by acute myeloid leukemia, myelodysplasia, non-Hodgkin's lymphomas, or multiple myeloma. Here most relevant results are summarized information stemmed studies. present report rather than provide a comprehensive review on hematologic neoplasms elderly, mainly reflects ‘philosophy’ deriving 15 years studies group field geriatric oncology/hematology. Elaboration ‘consensus’ view will represent challenge all investigators involved an important research.
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